This study assessed effectiveness of anti-corruption strategies that are implemented at the Directorate of Road Traffic and Safety Services (DRTSS). Specifically, the study analysed the concept of corruption, anti-corruption strategies, their effectiveness and challenges. The study adopted a mixed research method of collecting and analysing data. The study established that corruption still exists at the DRTSS despite devising several anti-corruption strategies. It was also found out that history and social cultural aspect of corruption in Malawi, the presence of middle persons and poor internet connection are the major causes of corruption at the DRTSS. The study found out DRTSS devised the following anti-corruption strategies: Fraud and Corruption Prevention Policy, computerized service delivery, among others. Among these strategies, computerization proved to be effective.